CF occurs because of mutations in the gene that makes a protein called CFTR (cystic fibrosis transmembrane regulator).
A person with CF produces abnormal CFTR protein — or no CFTR protein at all, which causes the body to make thick, sticky mucus instead of the thin, watery kind.
In someone with CF, however, the thicker mucus doesn't move as easily.
This thick, sticky mucus clogs passages in many of the body's organs and infection sets in.
The thick mucus also is in the pancreas — an organ that produces proteins called enzymes that flow into the intestine to support the body's digestion process.
Because the mucus can block the path between the pancreas and the intestines, people with CF have trouble digesting food and getting the vitamins and nutrients they need from it.
The thicker mucus has trouble moving out of the lungs, so bacteria can remain and cause infections.Doctors diagnose most kids with CF by the time they are 3 years old, but if someone has a milder form of the disease, it may not be diagnosed until that person reaches the teen years.Babies are usually tested if they are born with an intestinal blockage called meconium ileus, which is more common in CF infants. CF patients need to be vigilant in protecting their health so that they don't get sick. We have a lot in common, and it may be that we get together as a couple. I'm a carrier of the disease, and one uncle and cousin have it within my family. What is the likelihood that if I marry this girl my children would inherit cystic fibrosis? The reason I ask is that one of my friends suffers from it. I'm fairly healthy, growing and gaining wait at an average rate, and my PFT's are always high 90's low 100's. Cystic Fibrosis is incurable and fatal without a lung transplant. The ENT clinic said she had asthma but she has never had an attack. Hello I'm 14, 15 march first, and I have cystic fibrosis.People who are born with CF have two copies of the CF gene.In almost all people born with CF, one gene is received from each parent.CF can also affect the liver, the sweat glands, and the reproductive organs.Approximately 30,000 people in the United States have been diagnosed with CF, which affects both males and females.